Brain-to-gut signal via B12 may boost stress resilience, lifespan

Researchers have uncovered a direct highway from brain to gut that influences health. In a new study using worms, they found that Vitamin B12 metabolism in neurons triggers a serotonin-based signal. This signal travels to the gut, activating an stress-response pathway that boosts resilience and extends lifespan, providing a key model for diet's impact on aging.