12th Fail delves into real-life challenges faced by numerous aspirants tackling the UPSC entrance exam. Adapted from Anurag Pathak's book, the film narrates the compelling story of Manoj Kumar Sharma, an IPS officer from Chambal, who courageously embarks on an academic journey to reignite his ambitions amidst the daunting UPSC exam, symbolising the struggles of millions in pursuit of success.