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PCOS and leptin resistance makes weight loss harder: Expert
short by / on Monday, 23 February, 2026
With PCOS, your body's leptin hormone, the 'stop eating' signal, doesn't always function properly, so you feel hungrier and retain fat more easily, explains Dietitian Garima. This condition, called leptin resistance, often occurs alongside insulin resistance and disrupts hunger cues, making weight loss harder. Small habit changes and support can help break the cycle.