Indian equity indices opened in the red on Tuesday as heavyweights like Infosys, Eternal (Zomato) and Kotak Mahindra Bank were top losers in the BSE benchmark. At around 9:25 am, Sensex was down 444 points or 0.54 per cent at 81,985 and Nifty was down 105 points or 0.42 per cent at 24,817.