Sachin Tendulkar holds the record for scoring the most number of runs in India-Australia Test matches. Sachin scored 3,630 runs in 39 Test matches against Australia. He is followed by Ricky Ponting, who scored 2,555 runs in 29 Tests against India. He is followed by VVS Laxman (2,434 runs), Rahul Dravid (2,143), Michael Clarke (2,049) and Cheteshwar Pujara (1,893 runs).